tag:blogger.com,1999:blog-5339105318726100928.post4916086810409199080..comments2023-02-22T09:32:05.815-06:00Comments on Hormone Research Review: Estrogen dominance: it's not just a theoryEtsuko Uedahttp://www.blogger.com/profile/10014404635271515066noreply@blogger.comBlogger7125tag:blogger.com,1999:blog-5339105318726100928.post-69081047035059716052017-03-06T14:10:41.320-06:002017-03-06T14:10:41.320-06:00Reading your comment again, it looks like you were...Reading your comment again, it looks like you were still in transition, and your estrogen level was still not settled. The transition period is the most difficult time, which I did not experience because I had surgical menopause. Hopefully, it is all behind you by now and you can share your experience how you dealt with it. Etsuko Uedahttps://www.blogger.com/profile/10014404635271515066noreply@blogger.comtag:blogger.com,1999:blog-5339105318726100928.post-37994281305071684762014-08-02T17:11:02.811-05:002014-08-02T17:11:02.811-05:00Are you taking enough magnesium? Progesterone does...Are you taking enough magnesium? Progesterone does not work well if magnesium is lacking. Bleeding may also indicate a lack of some vitamins and mineral. During early post menopause, 0.025 mg /day seems enough for estradiol. I hope "Hormones: Dos and Don'ts" and "Hormone overdose: How can you tell?" will help.Etsuko Uedahttps://www.blogger.com/profile/10014404635271515066noreply@blogger.comtag:blogger.com,1999:blog-5339105318726100928.post-71912116974659384642014-08-02T16:49:05.206-05:002014-08-02T16:49:05.206-05:00Why do I not discuss estriol as an alternative est...Why do I not discuss estriol as an alternative estrogen? The short answer is I do not see the need. Estriol is one of the three main human estrogens (estradiol, estrone, and estriol). It is the end metabolite of estrone and estradiol, the weakest of the three and has very little stimulating effects, if any. That is why some doctors used it to avoid cancer risk when the cancer preventing role of progesterone was not known. Estriol is a poor substitute of estradiol, in terms of its ability to control menopausal symptoms and to maintain hormonal health. In terms of dosage, you only need a minute amount (25 to 50 micro gram/day) of estradiol, while you probably need 100 times more of estriol to control menopausal symptoms and only partially at that. In terms of the balance, since our body continues to make a good amount of estrone therefore estriol (its metabolite), I do not see the need. I would prefer to add DHEA to support the adrenal glands, which also boots testosterone, estrone, estriol, and reduces cortisol. <br />If reducing progesterone can take care of your sluggish and irritable feelings, that is great. But if it does not, you might want to try estradiol patch.<br />Etsuko Uedahttps://www.blogger.com/profile/10014404635271515066noreply@blogger.comtag:blogger.com,1999:blog-5339105318726100928.post-75671751185432906292014-07-29T20:53:50.119-05:002014-07-29T20:53:50.119-05:00Thank you for your helpful research and the annota...Thank you for your helpful research and the annotated references you provide.I have been struggling with postmenopausal problems and lupus for about 15 years now. I had been using vaginal estriol cream only, since I had bad experiences with oral estradiol and oral progestin in the past. Last week I started transdermal progesterone and transdermal estriol cream, and at the moment, as a result of the very high dose of progesterone and my reducing it, am having my first period in fifteen years. You are the only good source I have found for solid information on dosing and the effects of these. My question is why do you not discuss estriol as an alternative estrogen? I find it a gentler version than estradiol, which I now fear taking since a substantial oral dose drove my blood pressure dangerously high. Estriol does seem to improve my symptoms, especially now that I am taking the transdermal dose (2 percent), in addition to the vaginal dose (1 percent). I do feel sluggish and irritable, I think because of the progesterone, and am hoping that when I settle into the 25 mg dose once or twice per day, I might improve. Any thoughts you might have about this would be most welcome. ErnestineAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-5339105318726100928.post-50943773017468819572013-11-13T11:59:55.202-06:002013-11-13T11:59:55.202-06:00I'm approaching 52 and suffered from brain fog...I'm approaching 52 and suffered from brain fog, some insomnia, acid reflux, bloating and stomach issues years ago. After diagnosis of celiac disease, I feel that perhaps hormonal imbalances contributed to the affections of that disorder. I also wonder if certain gene expressions can be prevented if we begin considering hormone balance screening in the mid-40's. With the availability of information through blogs like yours, I feel that I can cautiously approach BHRT with minimal risk while I begin searching for a qualified BHRT doctor. Thank you very much for your thoroughness and clarity as well as your dedication to the well being and correct approach to these health matters. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5339105318726100928.post-19402378804501343922013-03-09T10:54:19.999-06:002013-03-09T10:54:19.999-06:00I was happy to find your blog and, based upon my p...I was happy to find your blog and, based upon my personal experience, I find much of what you are writing about is correct. I am 55 and had my last full period about 9 months ago. (A t least thats what i think it was.) I am using Vivelle patch (approx. .05 mg per day) along with Progest cream (approx. 15 mg per day). I'm still having constant water retention with all other symptoms (hot flashes, acne, irritability, bleeding, etc) coming and going. I can't find the correct balance in my hormone dosage. Should I add the DHEA, and how should I go about finding the correct dosages of estrogen, progesterone, and DHEA for my body? Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5339105318726100928.post-23703407437943570422010-06-25T00:26:10.470-05:002010-06-25T00:26:10.470-05:00realize some time ago an investigation similar in ...realize some time ago an investigation similar in which I learned a lot about this subject, I think is very good to learn about these things, thank you for sharing the information!cancerhttp://www.clinicalcancer.com/noreply@blogger.com